What is the typical first sign of pregnancy that most women notice?

The missed menstrual period is typically the first sign of pregnancy that many women notice. This symptom is often the clearest indication that fertilization and implantation may have occurred, especially for women who have regular menstrual cycles. When a woman becomes pregnant, hormonal changes typically result in the absence of menstruation, which prompts many to take a pregnancy test.

While nausea and vomiting, breast tenderness, and fatigue are also common symptoms of pregnancy, they often occur after the missed period has been recognized. Therefore, the missed menstrual period serves as a more immediate and observable change that women can identify as a potential sign of pregnancy. This is why it is considered the most typical initial sign when assessing a possible pregnancy.